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Fexofenadine

Therapeutic Group:

Anti Histamine

Presentation:

  • Fexfenadine 60: Each film-coated tablet contains Fexofenadine Hydrochloride USP 60 mg
  • Fexofenadine 120: Each film-coated tablet contains Fexofenadine Hydrochloride USP 120 mg
  • Fexofenadine 180: Each film-coated tablet contains Fexofenadine Hydrochloride USP 180 mg
  • Fexofenadine suspension: Each 5 ml suspension contains Fexofenadine Hydrochloride USP 30 mg

Description:

Fexofenadine is a second-generation, long lasting H1-receptor antagonist which has a selective and peripheral H1-antagonistic action. Fexofenadine (          ফে‌ক্সো‌ফেনা‌ডিন)blocks the H1-receptor and thus prevents activation of cells by histamine in the GI tract, large blood vessels and bronchial smooth muscle. This leads to relief of the allergic symptoms. Unlike most other antihistamines, Fexofenadine does not enter into the brain from the blood and therefore, does not cause drowsiness. Fexofenadine lacks the cardiotoxic potential, since it does not block the potassium channel involved in repolarization of cardiac cells.

Indications:

It is indicated for the relief of symptoms associated with seasonal and perennial allergic rhinitis and chronic idiopathic urticaria.

Dosage & Administration:

  • Adults:
    • Allergic rhinitis: 120 mg once daily or 60 mg twice daily
    • Urticaria: 180 mg once daily
  • Children:
    • 2-11 years: 30 mg (1 spoonful) or 5 ml twice daily
    • 6 months-2 years: 15 mg (1/2 spoonful) or 2.5 ml twice daily

Side Effects:

Fexofenadine is generally well tolerated. The most commonly reported adverse events are headache, drowsiness, nausea, and dizziness. The incidence of these events observed with Fexofenadine hydrochloride was similar to that observed with placebo.

Precautions:

Studies in the elderly, patients with hepatic impairment and patients with cardiac disease exposed to Fexofenadine showed no statistically significant differences compared to healthy individuals. As with most new drugs there is only limited data in the elderly and renally or hepatically impaired patients. Fexofenadine hydrochloride should be administered with care in these special groups.

Use in Pregnancy & Lactation:

  • In pregnancy
    Pregnancy Category B. There are no adequate and well controlled studies in pregnant women. Fexofenadine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
    Lactation
    It is not known if Fexofenadine is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Fexofenadine is administered to a nursing woman.

Contact Us

Bismillah Complex, 100 foot road, Madani Avenue, Notun Bazar, Badda, Gulshan-2, Dhaka, Bangladesh
info@medijobsbd.com
medijobsbd.com@gmail.com

Phone: 8801772622421

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